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1.
Journal of applied mathematics & computing ; : 1-24, 2022.
Article in English | EuropePMC | ID: covidwho-1624147

ABSTRACT

This paper proposes and analyses a new fractional-order SIR type epidemic model with a saturated treatment function. The detailed dynamics of the corresponding system, including the equilibrium points and their existence and uniqueness, uniform-boundedness, and stability of the solutions are studied. The threshold parameter, basic reproduction number of the system which determines the disease dynamics is derived, and the condition of occurrence of backward bifurcation is also determined. Some numerical works are conducted to validate our analytical results for the commensurate fractional-order system. Hopf bifurcations for the fractional-order system are studied by taking the order of the fractional differential as a bifurcation parameter.

2.
J Appl Math Comput ; 68(6): 4051-4074, 2022.
Article in English | MEDLINE | ID: covidwho-1620376

ABSTRACT

This paper proposes and analyses a new fractional-order SIR type epidemic model with a saturated treatment function. The detailed dynamics of the corresponding system, including the equilibrium points and their existence and uniqueness, uniform-boundedness, and stability of the solutions are studied. The threshold parameter, basic reproduction number of the system which determines the disease dynamics is derived, and the condition of occurrence of backward bifurcation is also determined. Some numerical works are conducted to validate our analytical results for the commensurate fractional-order system. Hopf bifurcations for the fractional-order system are studied by taking the order of the fractional differential as a bifurcation parameter.

3.
Chaos ; 30(11): 113119, 2020 Nov.
Article in English | MEDLINE | ID: covidwho-936204

ABSTRACT

The coronavirus disease 2019 (COVID-19) outbreak, due to SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), originated in Wuhan, China and is now a global pandemic. The unavailability of vaccines, delays in diagnosis of the disease, and lack of proper treatment resources are the leading causes of the rapid spread of COVID-19. The world is now facing a rapid loss of human lives and socioeconomic status. As a mathematical model can provide some real pictures of the disease spread, enabling better prevention measures. In this study, we propose and analyze a mathematical model to describe the COVID-19 pandemic. We have derived the threshold parameter basic reproduction number, and a detailed sensitivity analysis of this most crucial threshold parameter has been performed to determine the most sensitive indices. Finally, the model is applied to describe COVID-19 scenarios in India, the second-largest populated country in the world, and some of its vulnerable states. We also have short-term forecasting of COVID-19, and we have observed that controlling only one model parameter can significantly reduce the disease's vulnerability.


Subject(s)
COVID-19/prevention & control , Pandemics/prevention & control , COVID-19/epidemiology , COVID-19/transmission , Disease Susceptibility/epidemiology , Humans , India/epidemiology , Models, Theoretical , Quarantine/legislation & jurisprudence , Quarantine/methods , Quarantine/statistics & numerical data , SARS-CoV-2
4.
Chaos Solitons Fractals ; 136: 109889, 2020 Jul.
Article in English | MEDLINE | ID: covidwho-245484

ABSTRACT

As there is no vaccination and proper medicine for treatment, the recent pandemic caused by COVID-19 has drawn attention to the strategies of quarantine and other governmental measures, like lockdown, media coverage on social isolation, and improvement of public hygiene, etc to control the disease. The mathematical model can help when these intervention measures are the best strategies for disease control as well as how they might affect the disease dynamics. Motivated by this, in this article, we have formulated a mathematical model introducing a quarantine class and governmental intervention measures to mitigate disease transmission. We study a thorough dynamical behavior of the model in terms of the basic reproduction number. Further, we perform the sensitivity analysis of the essential reproduction number and found that reducing the contact of exposed and susceptible humans is the most critical factor in achieving disease control. To lessen the infected individuals as well as to minimize the cost of implementing government control measures, we formulate an optimal control problem, and optimal control is determined. Finally, we forecast a short-term trend of COVID-19 for the three highly affected states, Maharashtra, Delhi, and Tamil Nadu, in India, and it suggests that the first two states need further monitoring of control measures to reduce the contact of exposed and susceptible humans.

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